The Chemical Biology Consortium Sweden (CBCS) gathers expertise, resources, facilities and equipment for the identification and development of novel chemical tools to help you interrogate your particular field of interest. By drawing from our combined experience from both industry and academia, our talented group has provided input to more than 400 research projects during the past 5 years of operation, resulting in high-impact publications, innovations, patents and spin-off endeavors.
The most common project types carried out by CBCS and research groups in collaboration involve assay development and subsequent small molecule screening. Also follow-up work after a high-throughput screen, medicinal- or synthetic chemistry support can be carried out by/in collaboration with CBCS.
Our highly experienced Assay Development team works with a broad range of bioassay formats and has extensive knowledge in the intricate process of adapting novel bioassays from low-throughput to micotiter-based high-thoughput formats. We are equipped with multiple (liquid handling) work stations and readout systems to accommodate a broad range of screening technologies and sizes. Our screens range from isolated biochemical targets, to advanced primary cellular systems, phenotypic and high-content screens, plant biology, and whole organism screening in infectious diseases and cancer.
Access to synthetic organic and medicinal chemistry is a central component of chemical biology and critical for the further development of primary screening hits. Our chemistry teams consist of highly experienced, senior synthetic chemists with a background from both academia and the pharmaceutical industry, providing each project with unique insight into the molecular basis of the system being studied.