Uppsala University Drug Optimization and Pharmaceutical Profiling Platform (UDOPP)

The identification of drug candidates suitable for pre-clinical and clinical development involves not only obtaining sufficient potency on the relevant biological pathway, but also ensuring the compound’s ADMET (absorption, distribution, metabolism, excretion, toxicity) properties are consistent with obtaining efficacy in vivo. Through the use of a battery in vitro assays it is possible to optimize the pre-clinical properties, giving the chosen candidate drug the best possible chance of success. UDOPP uses state of the art technologies and cutting edge research to help projects optimize compound series and deliver candidate drugs of the highest possible quality.

Within UDOPP competences within  medicinal and physical chemistry, biopharmaceutics, bioanalysis, pharmacokinetics, formulations, cell and molecular biology and computational modeling are currently available, all of which are of major importance for a careful analysis of the ADMET profile of new drug candidates.

For more information about UDOPP, please visit their website here