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PRC evaluation criteria Overall Scientific Rationale and Impact Importance of CBCS efforts in the project Availability of (or validated plans for) secondary assays and test models Plans for validation of developed molecules Technical feasibility Resource requirements Publication strategy http://www.cbcs.se/gdpr daily 0.75 2023-10-13 http://www.cbcs.se/open-positions daily 0.75 2023-04-26 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/1675429554436-TXRVA5R45KV945WDW3UF/DSCF3093_SBF.jpg Open positions https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/0ad32529-1ff2-4771-b78a-bef5674c14ae/Kemi_2637_191118_MPN.JPG Open positions - No open positions CBCS Umeå http://www.cbcs.se/contact-ki daily 0.75 2022-01-27 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/ffa6c714-255b-40ef-8153-a95418cf0d54/Photo+Ulf+Sirborn Contact KI - Make it stand out Photo Ulf Sirborn https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/1549280385919-5PH5HAGUT9XLBAGZLBBR/ALG1_small.jpg Contact KI - Make it stand out Anna-Lena Gustavsson, Facility Director CBCS http://www.cbcs.se/contact-liu daily 0.75 2022-01-27 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/f32b4f3e-37a8-4b46-92f8-d44ba040aa8f/Maria+Lerm.jfif Contact LiU - Make it stand out Prof. Maria Lerm, CBCS Linköping http://www.cbcs.se/contact-bsl3 daily 0.75 2023-08-24 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/153dafb0-621a-4e18-b5bc-16bd43330aee/Marianna+Tampere+2.jpg Contact BSL3 - Make it stand out Whatever it is, the way you tell your story online can make all the difference. http://www.cbcs.se/contact-uu daily 0.75 2022-06-07 http://www.cbcs.se/contact-umu daily 0.75 2022-06-07 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/1639153996825-90C6V6UKUEIXK1870ENZ/Stina_bw.jpg Contact UmU - Make it stand out PhD Stina Berglund Fick, Co-Head of Unit, CBCS Umeå http://www.cbcs.se/contact-gu daily 0.75 2022-06-07 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/95f115db-b587-4de1-b59f-eb7d8d308f08/G%C3%B6ran+Karlsson.png Contact GU - Make it stand out Göran Karlsson, Director http://www.cbcs.se/contact-lu daily 0.75 2022-06-07 http://www.cbcs.se/staff-ki daily 0.75 2022-08-10 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/1588844515571-7OYJGIKJ5L7GI2U0BRSJ/ALG1.jpg Staff KI Anna-Lena Gustavsson, CBCS Facility Director https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/1588844661387-YF7AJ775YHI04JDIB99S/20110310-DSC_0101.jpg Staff KI Annika Jenmalm, SciLifeLab infrastructure director, Medicinal chemist https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/323a320c-017b-4a18-9dd8-cc5f84eb2c79/Brinton_Square.png Staff KI Brinton Seashore-Ludlow, Presicion medicine, AD & Screening https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/ca3a71c6-2afa-4b6b-90d6-cbdd878b00ab/20110310-DSC_0066.jpg Staff KI Hanna Axelsson, AD & Screening, CETSA https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/1588844868158-4XG2UZ4Q0517CTPBXNNH/Martin_Haraldsson.jpg Staff KI Martin Haraldsson, Medicinal and organic chemistry https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/153dafb0-621a-4e18-b5bc-16bd43330aee/Marianna+Tampere+2.jpg Staff KI Marianna Tampere, AD & Screening specialist, BSL-3 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/b13d542f-d41b-4138-86c9-a5212a694430/maria.jpg Staff KI Maria Adolfsson, Compound center, Acoustic dispensing expert https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/17e1d239-30a2-49f9-bf60-6a4fa17f85c8/Tobias+Koolmeister.jpg Staff KI Tobias Koolmeister, Medicinal and organic chemistry https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/e6ac43e4-e62e-406c-b8e3-1a8975da379a/Francesco+Massai.jpg Staff KI Francesco Massai, AD & Screening https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/33c56e96-2b60-47c1-a04a-65064560a688/Marjo.jpeg Staff KI - Make it stand out Marjo Puumalainen, BSL-3 facility, Biomedicum https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/62d275fc-7431-4bb7-ad3e-4cdae04c1a97/CC-logga.png Staff KI Åsa Slevin, Head of Compound Center https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/5b7475ca-38a8-4f41-bdfa-f315b0bfd8bd/CC-logga.png Staff KI Elisabeth Olsson, Compound Center, Chemistry & quality assurance expert https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/04899862-57e2-4ce2-a539-1e3230ea3804/Flavio-Ballante.jpg Staff KI Flavio Ballante, Medicinal chemistry and cheminformatics http://www.cbcs.se/staff-umu daily 0.75 2022-06-10 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/1588844527087-WZT4P1A2FHY5QYADTL7N/Chorell_Erik_6003_161115_MPN.jpg Staff UmU Erik Chorell, Facility director Umeå https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/105a72dd-5c4f-4a9a-9f18-a31ccc3a7046/stina_bw.jpg Staff UmU Stina Berglund Fick, AD & Screening https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/afaac85b-5911-46fc-8f6b-2d6d39cbf6c4/149341_16092014-dsc_0323.jpg Staff UmU Anna Eriksson, AD & Screening https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/35514dd5-468f-446f-b098-2e3603ac12b4/16092014-DSC_0335.jpg Staff UmU Weixing Qian, Organic chemistry https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/a7983c4c-1739-414e-80e8-7f646da91f09/Cecilia.jpg Staff UmU Cecilia Lindgren, Computational chemist https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/a74f2f2b-edab-4db9-8045-f80b2ac3d983/AD+%26+Screening.jpg Staff UmU TBA https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/8d5cd33b-ec9f-4fc1-b250-ade8646ea8b0/Medicinal+chemist.jpg Staff UmU TBA https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/10c95627-d106-4614-a90e-9e50a915efeb/AD+%26+Screening.jpg Staff UmU TBA http://www.cbcs.se/staff-uu daily 0.75 2022-06-10 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/a6177898-734a-4b9f-a476-230ef5db5ad2/Jordi-Carreras.jpg Staff UU Jordi Carreras Puigvert, Head of Unit, Cell profiling https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/3ff52127-e474-4e65-9fc5-847839778d69/ola+spjuth.jpg Staff UU Ola Spjuth, Platform scientific director, Computational pharmacology https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/97af6aa6-38d1-4877-8e60-7db7d7603eee/Morphological+cellprofiling.jpg Staff UU Malin Jarvius, Node manager, AD & Screening https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/1de90d29-6d15-4d73-afca-d9f74cba8cbb/Morphological+cellprofiling.jpg Staff UU Martin Johansson, Researcher http://www.cbcs.se/staff-gu daily 0.75 2022-06-10 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/baca20e7-3a8a-478d-b9e4-70d96e0c5462/G%C3%B6ran+Karlsson.png Staff GU Göran Karlsson, Director, NMR https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/e9caad68-0540-4643-b10a-3e004deb1b04/staff.jpg Staff GU Weixiao Wahlgren, Node contact, Structure-based drug design https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/eeeebb4e-8b0c-4bec-97ee-db9b858e4dbd/Ulrika+Brath.jpg Staff GU Ulrika Brath, Staff scientist, NMR https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/7ea29edd-55dd-4d96-ad68-0bd7dcfe4f5a/M%C3%A5rten+gr%C3%B6tli.jpg Staff GU Mårten Grötli http://www.cbcs.se/staff-liu daily 0.75 2022-06-10 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/978e989f-b0fb-4d2f-b337-3cbeef0f8051/Maria+Lerm.jpeg Staff LiU Prof. Maria Lerm, Node contact, BSL-2/BSL-3 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/aa618caf-8c10-4938-b444-f50dd591ecfb/Fredrik+Elinder-2021-LiU-6138.jpg Staff LiU Prof. Fredrik Elinder. Electrophysiology, Automated patch clamp https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/27b13a3d-d53d-452c-be65-0523cb83719f/Nina+Ottosson.jpeg Staff LiU Nina Ottosson, Electrophysiology, Automated patch clamp https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/a8bed2b2-dee5-4351-bfac-1144c50ac088/staff.jpg Staff LiU Eva Kristin Danielsson, BSL3, IncuCyte https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/e1a42fa9-2132-4c5c-8ca8-86b22d1c4541/staff.jpg Staff LiU Blanka Andersson, BSL3, AD&Screening http://www.cbcs.se/staff-lu daily 0.75 2022-06-10 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/01b1d9d4-57e8-423e-b58b-a7e0e20d5604/Roger+olsson.jpg Staff LU Roger Olsson, Platform scientific director, Node contact https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/2355c725-ef38-44f7-b68e-9938c862faed/Fredrik+Ek.jpg Staff LU Fredrik Ek, Node contact, small molecule screening https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/21814e2a-605b-4092-a9fd-03b96bd02527/Martin_Hjort2.jpg Staff LU Martin Hjort, Nanomaterials, engineering https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/5d0ff690-9281-4a73-a8c7-8d37a96997ca/staff.jpg Staff LU Ulf Nilsson http://www.cbcs.se/phenotypic-profiling daily 0.75 2022-06-21 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/08f89930-94e8-49d3-952f-21b2260ac52d/Phenotypic+profiling.jpg Phenotypic profiling Figure: a) Overview of cell profiling using the Cell Painting methodology. Cells are exposed to perturbations in the form of chemical substances in multi well plates. Images of cells are acquired and used to generate morphological cell profiles describing a wide range of the cells’ properties. These cell profiles or the original images can then be used in predictive modeling with e.g. Deep Learning methods. b) Experiments are carried out in our automated cell profiling lab. http://www.cbcs.se/bsl3-biomedicum daily 0.75 2022-08-10 https://images.squarespace-cdn.com/content/v1/5005c8ede4b0d377efc04f8e/e70aabe5-2b3f-4dfe-a925-46516fcd6bc3/Antivirals+at+bsl3+biomedicum.jpg BSL3 Biomedicum Figure 1. An example of high-throughput antiviral assays available at BSL3 Biomedicum. An image-based screening assay was developed in collaboration with Dr. Charlotte Stadler (Kaimal et al. biorxiv, 2022) and a cell viability assay in collaboration with Dr. Marianna Tampere.