The third ELRIG meeting on Advances in Cell Based Profiling in Drug Discovery will be held on the 22nd and 23rd of May 2019 at the AstraZeneca R&D premises in Gothenburg. This interactive 2-day event will host leading scientists from academia and industry to discuss current and future formats for cell based assays. This time the bi-annual meeting will be accompanied by a satellite meeting on Chemical Biology on May 24th, organized by key academic infrastructures in the Nordic countries. Our aim is to create an open and inspiring environment for networking between biologists and chemists, working towards a common view on expectations from our cell assays and their use for target identification, target validation and compound profiling purposes.
Cell based assays are utilized at all stages of drug discovery to explore disease mechanisms and to identify novel molecular therapeutics. Significant advancements are being made towards cell reagents and formats that provide a more accurate biological context, aiming at improving translation to human physiology/pathophysiology. Their implementation is much needed for improving success rates in drug discovery, but there are significant challenges associated with reliable and affordable reagent supply and validation of improved translational power to justify costs. This meeting serves to explore recent advancements and to discuss their practical implementation in drug and chemical probe discovery and validation.
The meeting program is developed around four key focus areas:
Precision Medicine in miniaturized formats
Phenotypic screening through advances in Precise Genome Editing
Multiplexed Screening with Single Cell Resolution
Target Engagement and Coherence with Functional Cellular Responses
ELRIG Chemical Biology Satellite Meeting- 24th May 2018